Xiaonan  received her Ph.D. in Genetics from Beijing Institute of Genomics, Chinese Academy of Sciences. During her Ph.D. study, she mainly focused on the molecular mechanisms underlying diseases, such as type 2 diabetes and chordoma, a rare bone tumor. Her PhD mentor, Professor Changqing Zeng, praised her for her outstanding performance in the experiments as a golden hand in the lab. Outside of the lab, Xiaonan likes swimming, ice skating, and decluttering. She also enjoys sharing her research with the public in the form of popular science. Xiaonan started her 2nd postdoc training in New York Genome Center in 2024.

 Selected Publications

1. Qian, J.*, Guan, X.*, Xie, B., Xu, C., Niu, J., Tang, X., Li, C.H., Colecraft, H.M., Jaenisch, R. Liu, X.S.(2023). Multiplex Epigenome Editing of MECP2 to Rescue Rett Syndrome Neurons. Science Translational Medicine Vol 15, Issue 679.
2. Shpokayte, M., McKissick, O., Guan, X., Yuan, B., Rahsepar, B., Fernandez, F., Ruesch, E., Grella, S.L., White, J.A., Liu, X.S., Ramirez, S. (2022). Hippocampal cells segregate positive and negative engrams. Nature Communication Biology. 5, Article number: 1009.
3. Wang, L.*, Guan, X.*, Hu, Q.*, Wu, Z.*, Chen, W.*, Song, L., Wang, K., Tian, K., Cao, C., Zhang, D., Ma, J., Tong, X., Zhang, B., Zhang, J., & Zeng, C. (2021). TGFB3 downregulation causing chordomagenesis and its tumor suppression role maintained by Smad7. Carcinogenesis, bgab022.